High-sensitivity multispeckle diffuse correlation spectroscopy
نویسندگان
چکیده
منابع مشابه
Time-domain diffuse correlation spectroscopy.
Physiological monitoring of oxygen delivery to the brain has great significance for improving the management of patients at risk for brain injury. Diffuse correlation spectroscopy (DCS) is a rapidly growing optical technology able to non-invasively assess the blood flow index (BFi) at the bedside. The current limitations of DCS are the contamination introduced by extracerebral tissue and the ne...
متن کاملMultispeckle diffusing-wave spectroscopy with a single-mode detection scheme.
We present a detection scheme for diffusing-wave spectroscopy (DWS) based on a two-cell geometry that allows efficient ensemble averaging. This is achieved by putting a fast rotating diffuser in the optical path between laser and sample. We show that the recorded (multispeckle) correlation echoes provide an ensemble averaged signal that does not require additional time averaging. Furthermore, c...
متن کاملHigh-pressure fluorescence correlation spectroscopy.
We demonstrate that a novel high-pressure cell is suitable for fluorescence correlation spectroscopy (FCS). The pressure cell consists of a single fused silica microcapillary. The cylindrical shape of the capillary leads to refraction of the excitation light, which affects the point spread function of the system. We characterize the influence of these beam distortions by FCS and photon-counting...
متن کاملHigh Frequency Sampling of TTL Pulses on a Raspberry Pi for Diffuse Correlation Spectroscopy Applications
Diffuse Correlation Spectroscopy (DCS) is a well-established optical technique that has been used for non-invasive measurement of blood flow in tissues. Instrumentation for DCS includes a correlation device that computes the temporal intensity autocorrelation of a coherent laser source after it has undergone diffuse scattering through a turbid medium. Typically, the signal acquisition and its a...
متن کاملResting-state functional connectivity measured by diffuse correlation spectroscopy.
Near-infrared diffuse correlation spectroscopy (DCS) is used to record spontaneous cerebral blood flow fluctuations in the frontal cortex. Nine adult subjects participated in the experiments, in which 8-minute spontaneous fluctuations were simultaneously recorded from the left and right dorsolateral and inferior frontal regions. Resting-state functional connectivity (RSFC) was measured by the t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurophotonics
سال: 2020
ISSN: 2329-423X
DOI: 10.1117/1.nph.7.3.035010